
Project Co-ordinator:
Prof. Leszek Kaczmarek
http://neurogene.nencki.gov.pl
l.kaczmarek@nencki.gov.pl
Nencki Institute
Warsaw, POLAND
Project Manager:
Ms. Marta Rucinska
m.rucinska@nencki.gov.pl
Nencki Institute
Warsaw, POLAND
Recruitment Co-ordinator
Prof. Alexander Dityatev
alexander.dityatev@dzne.de
Deutsches Zentrum fur
Neurodegenerative Erkrankungen
Magdeburg, GERMANY
Training Co-ordinator
Prof. Robert Pawlak
R.Pawlak@exeter.ac.uk
University of Exeter Medical School
Exeter, UK
Projects
The following 3 years PhD projects have been carried out within the Project:
(ESR means Early Stage Researcher; for the acronyms of the names of the institutions please refer to the home page)
- ESR1: Role of Matrix Metalloproteinase-9 (MMP-9) in schizophrenia-like behaviors (lead: NENCKI, partners: UNEXE, ETEC)
- ESR2: Role of Matrix Metalloproteinase-9 (MMP-9) in plasticity at synapses (lead: NENCKI, partners: UNEXE, MPG, SVIDA)
- ESR3: ECM-mediated regulation of GABAB receptors and schizophrenia (lead: DZNE-2a, partners: MPG, NENCKI)
- ESR4: Neurotrypsin and mental retardation (lead: DZNE-2a, partners: DZNE-2b, FMI)
- ESR5: The role of PAR-1/ECM interactions in neuronal remodelling (lead: UNEXE, partners: NENCKI, UCL, ETEC)
- ESR6: PAR-1 "ECM signalosome" and fear/anxiety (lead: UNEXE, partners: ENS, MPG, SVIDA)
- ESR7: MMP-9 and synaptogenesis upon learning in the hippocampus (lead: FMI, partners: NENCKI)
- ESR8: Normal variation in ECM-relevant gene families, MMP-9 and FragileX related genes: Contribution to neuropsychiatric phenotypes (lead: MPG, partners: NENCKI, DZNE-2a, SVIDA).
- ESR9: APP ectodomain and structural plasticity of dendritic spines (lead: DZNE-2b, partners: NENCKI, DZNE-2a, ETEC)
- ESR10: ECM and synapse dynamics (lead: ENS, partners: DZNE-2a, UCL, SVIDA)
- ESR11: Implications of miRNAs in several neurodegenerative disorders and their potential as therapeutic interventions (lead: SVIDA, partners: DZNE-2b, DZNE-2a)
There are also three postdoctoral positions running:
- ER1: Signal exchange between the ECM and astrocytes (lead: UCL, partners: NENCKI, UNEXE, DZNE-2a )
- ER2: Automated imaging platform to investigate the role of ECM on synapse number and function (lead: ETEC, partners: UCL, DZNE-2a, FMI, UNEXE )
- ER3: Parvalbumin neurons and PNN regulation upon enrichment: dissecting the neural correlate of enrichment (lead: FMI, partners: NENCKI, DZNE-2a)