ESR1
    ESR2
    ESR3
    ESR4
    ESR5
    ESR6
    ESR7
    ESR8
    ESR9
    ESR10
    ESR11
    ER1
    ER2
    ER3


Project Co-ordinator:

Prof. Leszek Kaczmarek
http://neurogene.nencki.gov.pl
l.kaczmarek@nencki.gov.pl
Nencki Institute
Warsaw, POLAND

 

Project Manager:

Ms. Marta Rucinska
m.rucinska@nencki.gov.pl
Nencki Institute
Warsaw, POLAND

 

Recruitment Co-ordinator

Prof. Alexander Dityatev
alexander.dityatev@dzne.de
Deutsches Zentrum fur
Neurodegenerative Erkrankungen
Magdeburg, GERMANY

 

Training Co-ordinator

Prof. Robert Pawlak
R.Pawlak@exeter.ac.uk
University of Exeter Medical School
Exeter, UK

ESR11: Implications of miRNAs in several neurodegenerative disorders and their potential as therapeutic interventions (lead: SVIDA, partners: DZNE-2b, DZNE-2a)

Adrian.jpg    Selected Student:           Adrian Posado Fernandez (Spain)
                         email:           adrian@stabvida.com

 

 

 

 

The project aims to identify miRNAs in blood that act as diagnostic and predictive markers for Alzheimer disease using a NextGenSequecing plataform.

 STAB VIDA information

1)Profile

STAB VIDA is a portuguese biotech company(www.stabvida.commainly focused on DNA and RNA-seq analysis and antibodies production. Our main applications are the diagnostic and personalized medicine for Alzheimer disease and Lung cancer.

 2Main publications:

Markoutsa E, Papadia K, Clemente CFlores O, Antimisiaris SG, 2012: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells, Eur J Pharm Biopharm, May;81(1):49-56. doi: 10.1016/j.ejpb.2012.02.006. Epub 2012 Feb 22

 

Canovi M, Markoutsa E, Lazar AN, Pampalakis G,Clemente C, Re F, Sesana S,  Masserini M, Salmona M, Duyckaerts C, Flores O, Gobbi M, Antimisiaris SG,  2011: The binding affinity of anti-A_1-42 MAb-decorated nanoliposomes to A_1-42 peptides in vitro and to amyloid deposits in post-mortem tissue, Biomaterials, Aug;32(23):5489-97. Epub 2011 May 6

 

Le Droumaguet B, Nicolas J, Brambilla D, Mura S, Maksimenko A, De Kimpe L, Salvati E, Zona C, Airoldi C, Canovi M, Gobbi M, Magali N, La Ferla B, Nicotra F,Scheper W, Flores O, Masserini M, Andrieux K, Couvreur P, 2012Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's diseaseACS Nano.Jul 24;6(7):5866-79. Epub 2012 Jul 2